Lewis Wing scored a second-half brace as Wycombe secured a thrilling 3-2 League One win to bring a halt to Derby’s 15-match unbeaten run in the league.
A 10th-minute Sam Vokes volley opened the scoring, before a close-range James Collins reply drew the visitors level.
Wing’s second-half double saw Wycombe move two goals ahead and – although a late Lewis Dobbin goal threatened a further twist – Wycombe held on for their fifth win in six at home.
Some 1,800 Derby supporters travelled for their side’s first meeting at Adams Park with fans, but saw Wycombe take the lead.
A counterattack ended at the feet of Brandon Hanlan, whose deflected shot looped into the air, with Vokes side-footing the ball home.
The second half saw Derby equalise through Collins, who converted David McGoldrick’s cross into the roof of the net before a late flurry of goals.
Only level for 10 minutes, a corner routine saw Wing’s goalbound shot deflect into the net before substitute Tjay De Barr set up the former Middlesbrough midfielder for his second, four minutes from time.
Derby had five minutes of stoppage time after Dobbin’s finish at the death, but Wycombe held on for maximum points.